| melting | compute the melting temperature of nucleic acid duplex | Mehr ... |
This program computes, for a nucleic acid duplex, the enthalpy, the
entropy and the melting temperature of the helix-coil
transitions. Three types of hybridisation are possible: DNA/DNA,
DNA/RNA, and RNA/RNA. The program first computes the hybridisation
enthalpy and entropy from the elementary parameters of each Crick's
pair by the nearest-neighbor method. Then the melting temperature is
computed. The set of thermodynamic parameters can be easily changed,
for instance following an experimental breakthrough. |
| melting-gui | graphical interface to compute the melting temperature of nucleic acid duplex | Mehr ... |
